Generic Name: Etoricoxib


Dosage Form: Tablet

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  • Presentation
  • Description
  • Indications
  • Dosage & Administration
  • Side Effect
  • Precautions
  • Contraindications
  • Drug Interaction
  • Storage



Starcox 60 Tablet  Each film coated tablet contains Etoricoxib INN 60 mg

Starcox 90 Tablet  Each film coated tablet contains Etoricoxib INN 90 mg


It is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, and antipyretic activities. It is a potent, orally active, highly selective cyclooxygenase-2 (COX-2) inhibitor within and above the clinical dose range. COX-2 has been shown to be primarily responsible for the synthesis of prostanoid mediators of pain, inflammation, and fever. Selective inhibition of COX-2 by Etoricoxib decreases these clinical signs and symptoms with decreased GI toxicity and without effects on platelet function.



For the relief of pain & inflammation in-
• Osteoarthritis, rheumatoid arthritis
• Other chronic musculoskeletal disorders 
• Acute gout
• Dysmenorrhoea
• Pain following dental surgery


Dosage & Administration

Route of administration: Oral.
Adult and adolescent over 16 years:In case of osteoarthritis, dysmenorrhoea, chronic musculoskeletal disorders, 60 mg once daily.In case of rheumatoid arthritis 90 mg once daily.In case of pain following dental surgery, acute gout 120 mg once daily.


Side Effect

Comon side effects: Side-effects may include dry mouth, taste disturbance, mouth ulcers, flatulence, constipation, appetite and weight changes, chest pain, fatigue, paraesthesia, influenza-like syndrome, myalgia.
Rare side effects: Low blood levels of sodium.



In patients with advanced renal disease, treatment with it is not recommended. Clinical experience in patients with estimated creatinine clearance of <30 ml/min is very limited. If therapy with it must be initiated in such patients, close monitoring of the patient's renal function is advisable. Caution should be used when initiating treatment with it in patients with considerable dehydration. It is advisable to rehydrate patients prior to starting therapy with it. The possibility of fluid retention, oedema or hypertension should be taken into consideration when it is used in patients with pre-existing oedema, hypertension, or heart failure. Independent of treatment, patients with a prior history of GI perforation, ulcers and bleeding (PUB) and patients greater than 65 years of age are known to be at a higher risk for a PUB. A patient with symptoms and/or signs suggesting liver dysfunction, or in whom an abnormal liver function test has occurred, should be evaluated for persistently abnormal liver function tests. If persistently abnormal liver function tests (three times the upper limit of normal) are detected, it should be discontinued. It should be used with caution in patients who have previously experienced acute asthmatic attacks, urticaria or rhinitis, which were precipitated by salicylates or non-selective cyclooxygenase inhibitors. It may mask fever, which is a sign of infection. The physician should be aware of this when using it in patients being treated for infection.



Etoricoxib is contraindicated in patients with know hypersensitivity to any of the ingredients. It is also contraindicated patient with active peptic ulceration or gastro-intestinal bleeding, Acute rhinitis, Oedema, Urticaria.


Drug Interaction

With medicine: Oral anticoagulants, diuretics and ACE inhibitors, Acetylsalicylic acid, Cyclosporin, Lithium, Methotrexate, oral contraceptives, Prednisolone, Digoxin, Ketoconazole & Rifampicin, have interaction with Etoricoxib.With Food & Others: Relevant data is not available.



Store in a cool and dry place, below 30 degree Celsius, away from light.