NORFEN (Diclofenac Sodium) is a non-steroidal anti-inflammatory agent with marked analgesic, anti-inflammatory and antipyretic properties. NORFEN   is enteric coated (acid resistant coating) with the result that the active constituent is not released until it has passed through the stomach. NORFEN SR capsule has got many advantages, because the frequency of drug administration is reduced, patient compliance can be improved and drug administration be made more convenient as well.

Rheumatoid arthritis, osteoarthritis, low back pain, injuries and manifestations of soft tissue rheumatism, ankylosing spondylitis, acute gout control of pain inflammation in orthopedic, dental and other minor surgery, juvenile rheumatoid arthritis, post operative pain, renal colic and other musculoskeletal disorders.

Adult: Enteric coated tablet: A total of 75-150 mg daily in two or three divided doses

Sustained release capsule: One capsule daily, taken whole with liquid, preferably during meal

Children: Enteric coated tablet: 1-3 mg/kg per day in divided doses.

Sustained release capsule: Not recommended.

Epigastric pain, nausea and diarrhea, headache and slight dizziness may be complained by some patients. These are often transient disappearing with comtinuation of medication. Occasionally skin rash, peripheral edema and abnormalities of serum transaminase have reported.

Very rarely reported side effects include activation of peptic ulcer, haematemesis or melena, blood dyscrasia (in course of extensive usage). There have been isolated reports of anaphylactoid reactions

Precaution should be taken in patients with symptoms/history of gastrointestinal disease, impaired hepatic, cardiac or renal function, pregnancy, porphyria and patients who are taking diuretics, anticoagulant or antidiabetics. During prolonged treatment, periodical monitoring of liver function should be carried out and blood counts are recommended. Possibility of hypersensitivity reactions to sodium disulphide particularly in patients with asthma.

NORFEN   is contraindicated in peptic ulcer, precious sensitivity to Diclofenac Sodium and in asthmatic patients in whom attacks of asthma, urticaria or acute rhinitis are precipitated by aspirin or other nonsteroidal anti-inflammatory agents with prostaglandin synthesis inhibiting activity.

Store in cool and dry place, away from light. Keep all medicines out of the reach of the children.