Generic Name: Nitazoxanide

Therapeutic Class: ANTHELMINTIC

Dosage Form: Tablet Suspension

View Prescribing

  • Presentation
  • Description
  • Indications
  • Dosage & Administration
  • Side Effect
  • Precautions
  • Contraindications
  • Drug Interaction
  • Storage



Diazox 500mg Tablet  Each film coated tablet contains Nitazoxanide INN 500 mg.

Diazox 30ml PFS  Each 5 ml suspension contains Nitazoxanide INN 100 mg.


Nitazoxanide, a synthetic antiprotozoal agent. Nitazoxanide is well absorbed from GIT. It interferes with the Pyruvate Ferredoxin Oxidoreductase (PFOR) enzyme dependent electron transfer reaction which is essential to anaerobic glucose energy metabolism. This results in cell swelling, membrane damage resulting in dysfunction of the parasite.



Diazox (Nitazoxanide), is indicated for the treatment of
1. Diarrhoea caused by Cryptosporidium parvum and Giardia lamblia.
2. Amebiasis and helminth infections.


Dosage & Administration

Age 1 - 3 years : 5 ml (100 mg) twice daily for 3 days
Age 4 - 11 years: 10 ml (200 mg) twice daily for 3 days
Age >12 years : 25 ml or 1 tablet (500 mg) twice daily for 3 days
The suspension or tablet should be taken with food.


Side Effect

Diazox (Nitazoxanide) is generally well tolerated. However abdominal pain, diarrhoea vomiting and headache have been reported rarely.



The pharmacokinetics of Diazox (Nitazoxanide) in patients with compromised renal or hepatic function have not been studied. Therefore, nitazoxanide must be administered with caution to patients with hepatic and biliary disease, to patients with renal disease and to patients with combined renal and hepatic disease.



Diazox (Nitazoxanide) is contraindicated in patients with a prior hypersensitivity to nitazoxanide or any other ingredient in the formulations.


Drug Interaction

Diazox (Nitazoxanide) is highly bound to plasma protein (>99.9%). Therefore, caution should be used when administering nitazoxanide concurrently with other highly plasma protein-bound drugs with narrow therapeutic indices, as competition for binding sites may occur (e.g., warfarin).



Store in a cool and dry place, away from light and moisture. Store the tablets, unsuspended powder, and the reconstituted oral suspension at 25°C. Once reconstituted suspension should be used within 7 days.