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Mupitas

Generic Name: Mupirocin

Therapeutic Class: Topical Antibiotic


Dosage Form: Ointment


View Prescribing


  • Presentation
  • Description
  • Indications
  • Dosage & Administration
  • Side Effect
  • Precautions
  • Contraindications
  • Drug Interaction
  • Storage

Presentation

Mupitas

Description

Mupitas is a novel topical broad spectrum antibiotic for the treatment bacterial skin infections. Mupitas ointment  contains Mupirocin 2% weight/weight. Mupirocin is a topical antibacterial agent, active against those organisms responsible for the majority of skin infections, e.g. Staphylococcus aureus, including methicillin-resistant strains, other staphylococci and streptococci. It is also active against Gram-negative pathogens, such as Escherichia coli and Heamophilus influenza.

 

Absorption & Excretion:

Mupitas penetrates intact human skin but the rate of systemic absorption appears to be low. Systemically absorbed Mupitas  is rapidly metabolized to the inactive metabolite monic acid and quickly excreted by the kidneys.

Mupitas

Indication

Bacterial skin infections, e.g. impetigo, folliculitis and furunculosis.

Mupitas

Dosage & Administration

Adults and Children: Mupitas should be applied to the affected area up to three times daily, for up to 10 days. The area may be covered with a dressing or occluded if desired. There is no long term experience of Mupitas in humans.

Mupitas

Side Effect

During clinical trials some minor adverse effects, localized to the area of application, were seen, such as burning sensation, stinging and itching. Cutaneous sensitization reactions have been reported rarely. Systemic allergic reactions have been reported with Mupitas ointment.

Mupitas

Precautions

This Mupitas formulation is not suitable for ophthalmic or intra-nasal use. When Mupitas is used on the face care should be taken to avoid the eyes. Mupirocin should be used with caution if there is evidence of moderate or severe renal impairment.

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Contraindications

Hypersensitivity to Mupirocin or other ointments containing any of its constituents.

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Drug Interaction

N/A

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Storage

Store in a cool and dry place, protected from light. Keep out of reach of the children.

Mupitas