Side effects with Cefuroxime is generally mild & transient in nature. Hypersensitivity reactions include skin rashes, urticaria, pruritus, drug fever, serum sickness etc. Very rarely occurs anaphylaxis. Gastro-intestinal disturbances including diarrhoea, nausea & vomiting are uncommon & occur with higher doses. Headache has also been reported. Treatment with Cefuroxime also report eosinophilia & transient increase of hepatic enzyme levels.