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Generic Name: Omeprazole

Therapeutic Class: ANTI-ULCERANTS

Dosage Form: Capsule

View Prescribing

  • Presentation
  • Description
  • Indications
  • Dosage & Administration
  • Side Effect
  • Precautions
  • Contraindications
  • Drug Interaction
  • Storage



Omiloc 20mg Capsule  Each Capsule contains Omeprazole BP mg as enteric-coated pellets.


Omiloc  (omeprazole), a substituted benzimidazole, is a specific inhibitor of the gastric proton pump (H+//K+-ATPase) in the parietal cell.Therefore it produces dose-dependent inhibition of both basal and stimulated acid secretion through blockage of (H+//K+-ATPase) enzyme irrespective of the stimulus. After oral administration,it is rapidly absorbed from the gastrointestinal tract. Omeprazole extremely binds to the plasma protein (about 95% and almost completely metabolized in the liver). Most of the part of omeprazole is eliminated in the urine and half life of it is 30-90 minutes



Omiloc® capsule is indicated for gastroesophageal reflux disease including reflux esophagitis, acid reflux disease, duodenal and benign gastric ulcers, Helicobacter pylori eradication regimens in peptic ulcer disease, prophylaxis of acid aspiration, Zollinger-Ellison Syndrome (ZES) and for the treatment of NSAID-associated gastric ulcers, duodenal ulcers or gastroduodenal erosions.


Dosage & Administration

Omeprazole should be taken before meal.


Side Effect

Omeprazole is well tolerated, nausea, diarrhea, abdominal colic, paresthesia, dizziness and headache have been stated to be generally mild and transient and not requiring a reduction in dosage.



When gastric ulcer is suspected, the possibility of gastric malignancy should be excluded before treatment with Omeprazole is instituted, as treatment may alleviate symptoms and delay diagnosis. Paediatric use of omeprazole is not yet established.



Omeprazole is contraindicated in patients with known hypersentivity to any of the components of the formulation.


Drug Interaction

Drug that are metabolized by cytochrome P-450 system such as cyclosporine, benzodiazepines have been reported to show interactions with Omeprazole. Omeprazole can delay the elimination of diazepam, phenytoin and warfarin. Reduction of warfarin or phenytoin dose may be necessary when Omeprazole is added to treatment. There is no evidence of an interaction with theophyline, propranolol or antacids.



Keep in a dry place, away from light and heat.