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Kumumox

Generic Name: Amoxicillin

Therapeutic Class: ANTIBIOTICS


Dosage Form: Capsule, PFS


View Prescribing


  • Presentation
  • Description
  • Indications
  • Dosage & Administration
  • Side Effect
  • Precautions
  • Contraindications
  • Drug Interaction
  • Storage

Presentation

Kumumox

Kumumox 500mg Capsule  

Description

Kumumox (Amoxicillin) is a broad spectrum semi-synthetic penicillin with bactericidal activity against a large number of gram-positive and gram-negative micro-organisms.

Kumumox

Indication

Kumumox (Amoxicillin) is indicated in the treatment of:
Respiratory tract and E.N.T infections :   Acute and chronic bronchitis, pneumonia, tonsilitis, pharyngitis, laryngitis, sinusitis and otitis media.
Urinary tract infections : Pyelonephritis, cystitis and urethritis.
Obstetrics and Gynaecological infections : Intra-abdominal sepsis, puerperal sepsis, septic abortion and bacteriuria  in pregnancy.
GI infection :      Typhoid and paratyphoid
Skin and soft tissue infection : Abscess, cellulitis and infected wounds
Venereal infections : Gonorrhoea and syphilis
Generalized infections : Septicaemia, meningitis, peritonitis, osteomyelitis and baterial endocarditis  
Kumumox (Amoxicillin)   may be used prophylactically in patients with high risk of developing endocarditis after surgical procedures. Therapy with Kumumox (Amoxicillin) may be instituted prior to obtaining results from bacteriological and susceptibility studies to identify the causative organisms and its susceptibility to Amoxicillin.

Kumumox

Dosage & Administration

Unless otherwise prescribed by the physician, the following dosage is recommended.
Adults:   500 mg (i.e. 1 capsule or 4 teaspoonful suspension) 8 hourly in severe infection. Normally 250 mg or 2 teaspoonfuls suspension 8 hourly.
Children 2-10 years         : 125 mg (1 teaspoonful suspension) 8 hourly
              Up to 2 Years       : 62.5 mg ( 1/2 teaspoonful) 8 hourly.     
In severe infections the dose may be doubled.
Some specific dosages :
Typhoid and para-typhoid.
Adults   : 4g per day in divided doses for 14-21 days.
Children               : 100 mg/kg/day in divided doses for 14-21 days.
Gonorrhoea : 3g as a single dose.
Syphilis : Depending on serological reactions and type of disease, 250mg 6 hourly for 1-5 months.
Simple acute urinary tract infection : Two doses of 3g each separated by an interval of 10-12 hours.
The excretion of the antibiotic may be delayed due to renal impairment. In such cases, it may be necessary to reduce the total daily dosage depending on the degree of impairment.

Kumumox

Side Effect

The side effects are usually mild and transitory. They may include diarrhoea, indigestion and occasionally urticarial or erythematous rash.

Kumumox

Precautions

As with any potent drug, periodic assessment of renal, hepatic and hematopoietic functions should be made during prolonged therapy. The possibility of super-infections with mycotic or bacterial pathogens should be kept in mind during therapy. If super-infections occur (usually involving Enterobacter, Pseudomonas or Candida), the drug should be discontinued and/or appropriate therapy should be instituted.

Kumumox

Contraindications

Kumumox (Amoxicillin) is contraindicated in patients hypersensitive to penicillins. Amoxicillin must not be used in patients with glandular fever.

Kumumox

Drug Interaction

Concurrent administration of probenecid delays the excretion of amoxycillin.

Kumumox

Storage

Store in a cool and dry place away from light and moisture. Keep out of the reach of children. Kumumox  Powder for Suspension should be reconstituted  immediately before use and  after reconstitution should be kept in cool place, if possible in a refrigerator. The reconstituted suspension should be used within 5 days if kept at room temperature or within 7 days if kept in refrigerator.

Kumumox